This drug refers to antibiotics that are used orally. It has a wide spectrum of active action . Suprax inhibits the formation of inflammatory pathogens in the body. The drug is resistant to bacterial enzymes that destroy the antibiotic, and therefore belongs to the 3rd generation .
Suprax treats various inflammatory infections, such as: diseases of the upper respiratory organs, otitis media, genitourinary infections, uncomplicated gonorrhea.
Remember that self-medication with antibiotics is not recommended. Only a doctor can determine and prescribe the correct dosage and treatment regimen .
- Storage
- Storage temperature
- Best before date
Composition and release form
The medicine is available in the form of easily soluble granules of white, less often cream color.
After contact with water, the granules transform into a suspension of uniform consistency with a strawberry smell and sweet taste. The drug contains additional and basic components that complement each other. The basis of the medicine is considered to be cefixime, the content of which does not exceed 5 mg per 100 ml of the finished product. The auxiliary ones are :
- sweetener;
- berry flavor identical to natural (strawberry);
- xanthan gum (stabilizer);
- sodium benzoate (preservative).
The granules are sold in hermetically sealed dark glass bottles. In addition to the bottle, the cardboard packaging contains a measuring spoon and instructions for use.
How to store the drug
Storage of the drug depends on the form of its release. Capsules can be stored at room temperature until the expiration date expires. The packaging reliably protects them, so they are not afraid of high humidity. The main thing is to avoid direct sunlight
The granules for preparing the medicine should also be kept away from light. As soon as they are diluted with water, the finished suspension is placed in the refrigerator and stored there for 14 days . If the product remains after this time, it is thrown away and then re-diluted if necessary.
Storage
Storage location depends on the dosage form. The undiluted suspension and capsules are stored at room temperature with other medications from the home medicine cabinet, observing standard conditions:
- Dry place.
- Room temperature up to +25 °C.
- Place inaccessible to children.
Storage temperature
In order to properly store the product, you need to study its instructions and do as the manufacturer recommends.
There are several storage rules:
- Reduced temperature from +5°C to +15°C.
- Room temperature not exceeding +25 °C.
According to the instructions for the drug containing granules for dilution, the finished suspension should be kept in a cool, dark place for 14 days . Capsules are stored at room temperature not exceeding +25 °C .
Best before date
The expiration date of the medicine is indicated on its packaging. Capsules can be used for 3 years from the date of their production.
Dry granules for diluting the suspension are similarly good for 3 years . The diluted suspension is stored in the refrigerator for a maximum of 14 days from the date of preparation and then discarded.
Do not ignore the storage recommendations indicated on the drug. Moreover, this dosage form is used exclusively in children, who are the most sensitive to spoiled foods and prone to various allergic reactions.
Indications
For a three-year-old child, Suprax suspension is prescribed for diagnosing diseases of infectious and inflammatory etiology that develop in the urinary system, respiratory and hearing organs. The medication is widely used in otolaryngology.
The main indications for use are::
- sinusitis;
- rhinitis;
- inflammatory processes in the ears and throat (otitis media, tonsillitis);
- urethritis;
- cystitis.
The drug has contraindications, against the background of which treatment with Suprax becomes impossible.
Features of application
Suprax is prescribed in childhood if more gentle methods of therapy have not had an effect or the disease has a complex form that requires treatment with antibiotics.
How to dilute the suspension
The suspension powder must be diluted to prepare a liquid medicine taken orally (by mouth).
Before diluting the suspension, you need to shake the bottle of granular powder well. Prepare 40 ml of distilled (or warm boiled) water in advance.
In order for the medicine to dissolve better in water, experts advise first diluting the powder with 20 ml of liquid and shaking the bottle well . Then pour in the remaining water and shake the bottle with the drug well again. In this way, it will be possible to obtain a homogeneous liquid.
If Suprax is diluted correctly, there will be no dry granules left at the bottom of the drug. Before each use, the medicine must be shaken so that the remaining product becomes homogeneous again.
Important! The drug must be diluted on the day of treatment, since its shelf life in diluted form is no more than 7 days, provided that the bottle of medicine is kept in the refrigerator.
Dosage
The treatment regimen for Suprax is determined by the attending physician, depending on all the features of the clinical picture.
If the Suprax suspension is diluted in children before the age of 18, then the medicine should be given according to the individual dosage calculation scheme: 8 mg/1 mg for dosing once a day.
The antibiotic should be diluted only on the day the therapeutic course begins, which will last no more than two weeks. The duration of treatment for children, as a rule, does not last longer than 5 days.
Antibiotics are potent drugs with an increased risk of side effects. The most common consequence of treatment with drugs of this group is a violation of the gastrointestinal microflora.
In order to protect the child from the negative consequences of antibiotic therapy, before preparing the Suprax suspension and starting to take it, the patient should be given probiotics, which help strengthen the protection of the microflora of the gastrointestinal tract.
Contraindications
Consultation with a pediatrician will help identify possible contraindications to the use of Suprax. Children three years old are prohibited from taking Suprax in the following cases :
- in case of individual intolerance to the main or additional components;
- with renal failure;
- with a history of pseudomembranous colitis.
Despite the absence of absolute contraindications in a small child, the use of Suprax in children should be cautious.
pharmachologic effect
An antibiotic called Suprax is the first among third-generation antibiotic drugs that can be taken orally.
Since the substance is Cefixime, the medicine has a wide spectrum of activity. The mechanism in the drug is bactericidal, and due to it, the disease is suppressed by affecting each cell individually. If we compare a similar drug with its other analogues, it is more resistant to the so-called beta-lactamase. This component is a kind of enzyme that, when interacting with a drug, makes its properties neutral.
Based on what is prescribed in the instructions, a drug called Suprax is capable of inhibiting such negative substances as streptococci, as well as E. coli, and so on. It is important to note that Pseudomonas aeruginosa and most of the staphylococcus species have already adapted to the effects of such a drug. The bioavailability of such a medicine is about 50 percent. In most cases with antibiotics, eating reduces their effect, but not in our case.
Compared to other antibiotics of earlier generations, it is Suprax that has the longest so-called half-life. Based on this, the number of doses is not too large; one dose per day will be enough. This is very convenient for busy people or for children. This drug is also distinguished by its excellent penetration into the disease itself, due to penetration into every cell.
About half of the medication is usually excreted in the urine. Due to this, the drug is called one of the best in terms of treatment of the urinary tract. 10 percent of the drug is excreted into bile. If you use a similar antibiotic together with so-called diuretics, the elimination will slow down. After analyzing the reviews about this drug, we realized that it does not have a depressing effect on the microflora of the body. While other similar drugs have a serious effect on the intestinal microflora.
Dosage and method of administration
The dosage of Suprax for children aged 3 years is determined individually, based on the child’s weight. The instructions for use contain approximate doses; it is not recommended to rely entirely on the annotation. The recommended therapeutic dose for children 3-4 years old is 5 mg of the active ingredient (equivalent to 100 ml of suspension) per 10 kg of weight. For convenience, the daily dose can be divided into 2-3 doses (30-50 ml at a time).
Using a measuring spoon, measure the required amount of powder and dissolve it in 100 ml of water. Place the container with the suspension in a cool place for 5-7 minutes until the powder is completely dissolved. Gently shake the prepared emulsion and give it to the child to drink. Thanks to the berry aroma and sweet taste, there is no need to drink syrup. The period of admission is 5-10 days. If necessary, the course of treatment can be repeated after 7 days . The presence of food in the stomach does not affect the rate of absorption, so the medicine can be taken during meals and after meals.
Best before date
The antibiotic Suprax is available in three forms:
- Dispersible tablets. Shelf life – 3 years;
- Capsules. Shelf life – 3 years;
- Granules for preparing a suspension. Provided the original packaging is intact, the shelf life is 3 years. The diluted suspension is stored for no more than 10 days.
The release date is indicated on the bottle, blister and cardboard packaging.
Temperature fluctuations have a detrimental effect on the active substance cefixime. In cold and heat, chemical reactions accelerate and cefixime is destroyed. This leads to a reduction in shelf life to 5-7 days.
Provided proper storage and packaging integrity, the drug can be used 5-10 days before the expiration date.
Defective and expired drugs can be distinguished by the following characteristics:
- no expiration date on the packaging;
- lack of instructions for use;
- the batch number on the packaging differs from that indicated in the instructions;
- poor quality packaging;
- tablets crumble;
- there is no “H808” inscription on the capsules;
- granules are powdery or stick together at the bottom of the bottle;
- unpleasant smell.
At the end of their shelf life, tablets and capsules become brittle and brittle. The finished suspension precipitates and acquires an unpleasant odor.
After the final storage date, the antibiotic Suprax cannot be used. This will burn and lead to an allergic reaction and poisoning.
The long shelf life of Suprax is due to the fact that the active ingredients retain their chemical formula without interaction with air and water.
Side effects
Some allergic reactions of the human body may occur. From the digestive system, side effects are expressed as:
- dry mouth;
- anorexia;
- nausea;
- vomiting;
- diarrhea;
- flatulence;
- abdominal pain;
- dysbacteriosis;
- liver dysfunction.
Leukopenia, neutropenia, hemolytic anemia, and interstitial nephritis may occur. There may be dizziness and headaches.
Instructions for use
As a rule, doctors prescribe the medicine in the form of a so-called suspension, the dose of bark is about 8 mg. You can split this dose into two doses, but 4 mg each. If the children are older and are already from 5 to 11 years old, then the proportions must be increased to 10 mg. At a time when up to one year the amount of the drug should be up to 4 ml.
On average, antibiotic treatment should last approximately 10 days. If the patient is already an adult and his body weight is more than 50 kg, then the medication should be about 400 mg once a day, or this amount of the drug should be divided into two doses. For various diseases, the course should last at least one week, and in some cases at least ten days.
There are cases when a patient is prescribed this drug, but he has kidney problems. In this case, it is recommended to reduce the dose by about 25 percent.
It is also important to prepare the suspension correctly. First of all, you need to remove all the contents of the bottle. You need to add about 40 ml of boiled water to the medicine. Shake the contents once, and after a certain time again. Next, leave the so-called suspension for five minutes.
Before you use the prepared medicine, you will need to shake it so that the sediment rises to the top and the medicine is more concentrated. The drug should be stored at a temperature not lower than 14 degrees and not higher than 25. After preparation, the shelf life of the medicine is about two weeks.
Analogues of the drug Suprax
The list of substances with a similar functioning element is not too long and contains only 3 drugs:
- Ixim Lupine in the form of granules for making a suspension. The price starts from 355 rubles. Children under 12 years of age are prescribed a dose of 8 mg/kg body weight 1 time per day or the dose can be divided into 2 doses. It is also used in pediatrics to treat children from six months of age.
- Cefix (granules for making a suspension) is another affordable analogue of Suprax for a child (275 rubles). It expresses antibacterial activity aimed at gram-positive and gram-negative microflora agents. In addition, like Suprax, it does not have a great effect on the formation of pseudomonas, listeria, and staphylococci. But Cefix is effectively used in the treatment of tracheitis and acute intestinal infections, unlike the original.
- Cefspan (from RUB 581). The children's release model involves fine-grained granules for making a suspension. The drug inhibits the combination of murein (cell wall protein) of pathogenic microorganisms. Unlike Suprax, it is prescribed to cure scarlet fever in children from 6 months.
In total, there are few drugs in the world that have such an effect. This type of drug has a positive effect on the body, but it is also important to monitor side effects.
