Pyrantel: instructions for use for children

Composition and release form

Pyrantel suspension is an anthelmintic drug , i.e. it is aimed at combating worms.

Its active ingredient is pyrantel (250 mg in 5 ml of the drug), which affects the smooth muscles of intestinal nematodes, blocking the sensitivity of helminths.

The product shows very good results in the fight against a number of parasites: Necator americanus, Enterobius vermicularis, Trichostrongylus colubriformis and others.

In addition to pyrantel, the suspension includes the following components:

sorbic acid - 5 mg;
sorbitol solution 70% - 1 ml;
propylparaben - 5 mg;
sucrose - 1150 mg;
xanthan gum - 7.5 mg;
polysorbate 80 - 0.025 mg;
purified water - about 5 ml.

The suspension contains flavorings, so the product has a pleasant taste , which is important for children who are difficult to persuade to take the medicine.

There are two flavors in total:

chocolate - 1 ml. The composition includes water, propylene glycol, caramel coloring, natural aromatic components;
“Ice cream” flavoring – 0.015 mg. The composition includes almost the same components as in the previous dye, except for the flavor itself, which forms the taste.

Pyrantel suspension is available in dark glass bottles with a capacity of 15 ml. The kit also includes a measuring cap, and the packaging of the drug itself is made of cardboard.

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Pyrantel - instructions for use for children: tablets and suspension

The antiparasitic drug Pirantel 250 is one of the best compounds that help with helminthic infestation in adults and children.

For babies, Pyrantel suspension is available, indicated for use from 6 months.

The effectiveness of anthelmintic therapy is achieved due to the fact that the tablets cause disruption of the nervous system of nematodes, due to which the worms leave the body naturally.

Composition and description

Tablets for worms, the composition of which is as follows:

pyrantel pamoate 750 mg – main substance;
starch, gelatin, acacia gum, magnesium stearate, aerosil, methyl parahydroxybenzoate – excipients.

Pirantel 250 tablets are available in 3 pcs. – strips (1), in a cardboard box with an annotation included. Pyrantel suspension for children contains 50 mg of the active ingredient per 1 ml. Reviews of the suspension and tablet form of the drug confirm the high effectiveness of the drug for enterobiasis, necatoriasis, and hookworm disease.

Important! Pirantel works best against worms in the early stages of infestation and against sexually mature helminths. The drug has no effect on the larvae and eggs of parasites.

Instructions for use of the drug

The use of Pyrantel is indicated for the treatment of:

ascariasis;
hookworm disease;
necatoriasis;
trichocephalosis.

Only your doctor will tell you how to take Pirantel correctly; the instructions for use of Pirantel only recommend approximate dosages. Pyrantel tablets are taken:

inside after meals;
The tablets should be chewed, swallowed and only then washed down with water.

Important! The dosage of the medicine depends on the type of helminthiasis, the severity of the lesion, the age and weight of the patient.

How to take Pirantel tablets for adults:

with a weight of 75 kg. take 4 tablets once;
patients weighing up to 75 kg – 3 tablets once.

Instructions for use for children:

over 12 years old – 750 mg once (15 ml suspension);
6-12 years – 500 mg once (10 ml);
3-6 years – 1 tablet or 250 mg (5 ml) once.

Pyrantel is given to young children based on weight: 10 mg per kg. If the baby weighs 15 kg, the medicine is taken at a dose of 125 mg.

Pyrantel suspension is taken according to the following regimen:

6-24 months – 2.5 ml;
2-6 years – 5 ml;
6-12 years – 10 ml;
from 12 years old and weighing up to 75 kg – 15 ml.

For adult patients weighing more than 75 kg, 20 ml or more can be taken, depending on the severity of the invasion. How to take medicine depending on the type of disease:

isolated ascariasis – 1 time per day;
severe form of necatoriasis - once a day for a course of 2 days;
hookworm - a course of 3 days in the dosage prescribed by the attending physician.

Contraindications

Pyrantel should absolutely not be taken during pregnancy. The aggressive component of the drug has a negative impact on the health of the unborn child.

Despite the fact that the drug is prohibited during pregnancy, you can take an antiparasitic drug while breastfeeding, but only with great caution and after consulting a doctor.

During therapy, lactation should be stopped. The medicine is contraindicated:

children under 3 years of age (tablet form);
for autoimmune diseases.

Important! Caution should be exercised in patients with renal and hepatic insufficiency. For children and elderly patients, it is better to buy a suspension.

Side effects

Tablets and suspensions have the most positive reviews. Despite the fact that Pirantel cannot be taken during pregnancy due to the aggressiveness of the main substance, the drug is well tolerated by patients. Reviews of parasitologists about Pirantel warn that all side effects are observed only in case of an overdose of the drug. Symptoms:

headache, sleep disturbances;
decreased hearing acuity;
itching, skin rashes;
abdominal pain;
confusion;
hyperthermia;
hallucinations.

Important! To prevent side effects, you should definitely consult your doctor. The doctor will explain how to give Pyrantel to a child if the medicine is only available in tablets, how to take Pyrantel for pinworms during lactation and other points.

Analogs

The active component is present in medicines: Helmintox, Nemotsid. Based on antiparasitic properties, you can choose Pirantel Decaris, Albendazole, Piperazine. If the choice is Vermox or Pyrantel, then you should remember: Vermox kills parasites, the second drug paralyzes nematodes. Therefore, when treating with Vermox and other antiparasitic drugs, it is necessary to take sorbents.

Advice! Pirantel can be given for prevention to children and adults. The drug should be taken according to the patient’s weight in the dosage recommended above.

Contraindications

Pirantel has contraindications for use.

The drug should not be taken by those who have demonstrated hypersensitivity to the active substance - pyrantel.

If a person suffers from myasthenia gravis, the medicine is contraindicated for him.

Myasthenia gravis is an autoimmune disease that causes muscle fatigue.

The drug is easily tolerated by children , but doctors do not advise giving it if the child is less than six months old.

Use with caution in children with liver failure. Taking the drug must be agreed with your doctor, who will select the right dosage.

Pyrantel side effects in children

The instructions for use of Pyrantel for children indicate that the active substance of the drug causes muscle spasm and subsequent paralysis of roundworms. Dead organisms are eliminated through the intestines. The drug is prescribed after diagnosing ascariasis, enterobiasis, hookworm infection, necatoriasis, and, less commonly, for trichuriasis.

The drug is not prescribed against parasites of other species. Firstly, it is caused by the localization of the action. Secondly, many parasites are able to attach themselves to the walls - mass death causes intoxication. Therefore, Pirantel is prescribed only after diagnosis or suspicion of a specific type of parasitic organism.

Pyrantel is produced in the form of tablets and suspensions. Available only by prescription.

Symptoms of infection

The presence of parasites negatively affects the development of the child, including inhibition of mental development. Signs of parasite infestation:

weakness;
weight loss;
change in skin color;
temperature increase;
itching in the anus (one of the clearest evidence);
sleep disorders;
allergies and rashes;
headaches and dizziness;
dysfunction of the gastrointestinal tract;
frequent illnesses (ARVI, bronchitis, tonsillitis).

Note! It is strictly contraindicated to prescribe the drug on your own! The product, like other drugs aimed at combating parasites, has slight toxicity.

Pyrantel suspension - instructions for use for children

When used for a child under 2-3 years of age, take special care.

Pyrantel liquid - instructions for use for children:

6 months to 2 years – ½ scoop. Spoon volume – 5 ml.
2-6 years – 1 spoon.
6-12 years – 2 spoons.
12 years and older – 3 spoons.

The proposed scheme is used by doctors for ascariasis and enterobiasis and is a one-time dose. Repeated use is prescribed 3 weeks after the examination.

The treatment regimen for hookworm infection involves strict control and a course of at least 3 days. In this case, 10-12 mg per 1 kg of child’s weight is prescribed for three days. Necatoriasis is considered even more dangerous, so the dosage is increased to 20 mg per 1 kg of weight. Duration of treatment – 2 days.

The drug is taken during or after meals, drinking water.

Pirantel suspension - instructions for use for children and price

The cost of a bottle of suspension depends on the manufacturer. In most cases, the price ranges from 30 to 70 rubles per 15 ml of the drug. The 10 or 15 ml bottle comes with a 5 ml measuring spoon.

Pirantel suspension - instructions for use for children and reviews

Pyrantel is prescribed against helminths, as it has:

wide spectrum of action;
high efficiency;
the ability to select a treatment regimen for a specific case;
possibility of receiving small children;
low price.

There are side effects, but with proper treatment they can be mitigated. That's why doctors' reviews of Pirantel are good.

Patients also have a positive attitude towards the drug. Only in isolated cases are there negative reviews of Pirantel caused by the reaction of the child’s body. There are minor problems with the digestive system. Liquid Pyrantel is used at any age.

Pirantel tablets - instructions for use for children

This release form is intended for children and adults over 3 years of age. Like the suspension, the tablets are taken during or after meals. It is necessary to chew the drug thoroughly and wash it down with water.

Pyrantel-250 tablets instructions for use for children:

3-6 years – 1 tablet.
6-12 years – 2 tablets.
12 and older – 3 tablets.

Pirantel syrup - instructions for use for children

Syrup is a suspension. Children's Pyrantel in liquid form is flavored to make it easier for young children to use. Chocolate and fruit flavors are used.

Syrup dosage for children:

2.5 ml for children from 6 months to 2 years;
5 ml - for ages from 2 to 6 years;
10 ml - for 6-12 years;
15 ml - 12 years and older.

Pirantel syrup is given to children during or immediately after meals. If necessary, the drug is used again, after passing the necessary tests and consulting a doctor.

Pirantel 250 - instructions for use for children

In most cases, a one-time dose of the drug is prescribed. Repeated use is recommended after 3 weeks. This is explained by the fact that the substance affects adult and immature roundworms, but is absolutely powerless against their larvae and eggs. You can take the medicine at any time, but experts recommend doing it before bed.

Alternative schemes are selected depending on the goals set. There is a chance that the doctor will prescribe a course for several days. This will reduce the dosage. The optimal ratio is 10 mg per 1 kg of child weight.

One tablet contains 250 mg of pyrantel. Depending on the manufacturer, the composition of excipients varies.

For children under 7 years of age, it is recommended to crush the tablet, mix it with water, and give it to the child to drink.

Source: https://vmassazh.ru/info/pirantel-pobochnye-dejstvija-u-rebenka/

How the drug works

The drug is a suspension, i.e. syrup, which is an additional advantage. Children tolerate the medicine more easily, and drinking it is much more pleasant than taking pills.

The active substance included in the suspension enters the intestines and has a paralyzing effect on round parasites - nematodes, pinworms, roundworms and whipworms.

The peculiarity of Pirantel is that there is no need to prepare the child in any way before taking it.

Thanks to its active action, worms move very slowly in the intestines and are eliminated from the body naturally.

There is no need to take additional steps to remove parasites: they come out of the intestines themselves when the baby goes to the toilet.

The active ingredients of the drug penetrate the liver through the blood.

Even if this proportion is small, parents must take this fact into account when giving their child this medicine.

The remainder of the drug is excreted from the body naturally, i.e. through urine and feces.

Pyrantel side effects in children

For Pirantel, the instructions for use for children state that the product is intended to combat helminthic infestations and contains information on dosage, indications, possible side effects, contraindications and overdose. This product must be used as prescribed by your doctor, following all recommendations, frequency of use and dosage.

Efficacy of the drug

Currently, the prevalence of helminthic disease among young children is rapidly increasing, which is associated with poor hygiene. This disease causes unpleasant symptoms, the presence of which can immediately detect pathology. The most common parasites are roundworms, pinworms, whipworms and some others.

Pyrantel is widely used to combat them. This medicine is synthetic and has proven itself on the positive side. The drug is considered an anthelmintic; it is aimed at suppressing the reproduction of parasites and their further development.

The active substance Pyrantel is a synthetic substance pamoate, which helps stop the nervous and muscle process, provides paralysis of helminths, destroys them and removes them from the body. The drug effectively fights many worms and can be used by both children and adults.

Due to the high therapeutic effect, complete removal of helminthic infestation from the body is ensured, and re-development of the disease occurs quite rarely. But in addition to the positive properties of the drug, it should be used to treat children only as prescribed by a medical specialist, since it has contraindications and side effects.

Forms of release of the drug

For ease of use in childhood, Pirantel is available in various dosage forms. Thanks to this, use is possible even for infants from 6 months.

Pyrantel tablets

The following forms of Pyrantel are distinguished:

Pills . They are yellow capsules with no special shell and one division. The composition includes active and auxiliary components. The active substance is pyrantel, auxiliary components are gelatin, talc, starch, magnesium stearate, colloidal silicon dioxide, sodium starch gluconate and other components in small quantities.
Suspensions are a viscous, jelly-like yellow mass for internal use in an amount of 50 ml. 5 ml of the medicine contains the active component - pyrantel, excipient - sucrose, sodium saccharin, sodium chloride, citric acid, chocolate essence, sorbidol, purified water, sodium carboxymethylcellulose, methylparaben and sodium propylparaben.
The syrup is a liquid medicine of Pyrantel. It is best used for small children, as it has a pleasant sweet taste and smell. The composition also contains auxiliary and active substances, which, when interacting together, help in the treatment of helminthic infestation. The dosage of the drug is prescribed by the doctor.

Any of the listed forms of Pyrantel has a positive effect on the body during therapeutic effects, helps destroy parasites and has a gentle effect on their elimination.

Indications for use of the medication

The drug Pirantel is considered the most common for the treatment of helminthic infestation. It is capable of destroying many forms of helminths, affecting their nervous and muscular systems.

Disease lurks in the sand

The drug can be indicated for children and adults due to the presence of several forms of the drug. It is mainly used for the following diseases:

Ascariasis is a common pathology, expressed by vivid symptoms.
Necatoriasis - occurs in children and adults, symptoms appear almost immediately.
Enterobiasis - occurs when hygiene is not observed, and is more common in childhood.
Hookworm - develops due to parasitic worms, the pathology is determined by unpleasant symptoms.
Trichocephalosis . Like other diseases, it mainly occurs in children and appears due to poor hygiene.

It is not advisable to start therapy on your own, as the medicine has contraindications and can cause side effects. Before use, you need to undergo an examination, take a stool test, on the basis of which the doctor makes a diagnosis and prescribes further treatment, according to the type of parasites, the patient’s age and other characteristics.

What are the contraindications for use?

The drug is quite effective and helps treat many forms of helminthic infestation.

But in addition to its positive properties, it has contraindications, therefore, before using it for therapy, you should consult a doctor.

It is not advisable to use it independently, because depending on the age and type of parasite, an individual dosage and frequency of use are prescribed.

No need for pills!

Contraindicated for use in children with the following pathologies:

Myasthenia gravis . A chronic disease characterized by damage to the nervous and muscular systems is caused by constant weakness, malaise, and dysfunction of muscle activity.
Individual intolerance to one of the components of the medicinal substance.
Pathological processes of the liver ( liver failure and others).

In addition, the age of the child may be considered a contraindication, so children from 6 months are allowed to use the suspension, and from 3 years to use the medicine in tablet form.

Side effects

If medical recommendations are not followed or a larger dose of the drug is taken, side effects may occur:

Severe headaches, dizziness.
Lack of clarity of consciousness.
The appearance of hallucinations of various types.
Intestinal dysfunction (loose stools, constipation).
Pain in the epigastric region.
Allergic reactions, expressed by skin rashes, redness, itching, swelling. In severe cases, drug intoxication may cause anaphylactic shock.
Increased body temperature, prolonged fever.
Nausea, maybe vomiting.

Often the severity of side effects is temporary. But still, if one of the above symptoms occurs in a child, it is necessary to stop using the medicine and visit a specialist. Because, depending on the characteristics of the body, severe intoxication can develop, leading to serious complications.

How to use it correctly for children

How to take Pirantel in childhood? Before using this product, you should consult with your doctor, who will determine the dosage and frequency of administration. The amount of the prescribed drug depends on the baby’s body weight and the form of helminthic infestation, so stool is first collected for examination and other procedures.

Consumption of Pyrantel syrup

Depending on the dosage form of the drug, the instructions vary slightly:

Taking pills . They are often prescribed to school-age children and adults, but are also allowed for children over 3 years of age. They are prescribed strictly by a medical specialist, he sets the amount of intake, dosage, based on the weight of the child. To treat helminthic infestation, children over 3 years old need 1 tablet per day. If a child is over 3 years old - 1-2 tablets, from 12 years old 3-4 tablets are prescribed per day. For effective therapy, chew the tablet well and drink a glass of water.
Suspensions are approved for use by children from 6 months of age; in this case, body weight is also taken into account in order to calculate the dosage and frequency of use. According to the instructions, children from six months to 2 years old are recommended to take half a cap of syrup, from 2 to 6 years old - 1 capful, up to 12 years of age - 2 measuring caps, over 12 years old - 3 measuring caps per day. Often, when worms are detected, a single dose is sufficient; if the parasites are highly active, the duration of administration is 3 days; if this is not enough, the course is extended to 5 days. Pyrantel suspension for children is also used for preventive purposes.
Use of syrup - if other dosage forms of Pyrantel are not suitable, syrup is prescribed by your doctor. It has a positive effect on the body and helps suppress the activity of helminthic infestations. Thanks to its pleasant taste and smell, it is well used by children. For convenience, you can add it to food. The dosage is calculated based on the patient’s body weight; children are prescribed 10 ml per 1 kg of weight.

Source: https://ParazitHelp.ru/parazity/pirantel-pobochnye-jeffekty-u-detej.html

The article will provide instructions for the Pirantel anti-worm suspension.

Infection with helminths is common in childhood, as children may put dirty hands in their mouth, eat vegetables and fruits that have not been washed, drink raw water, or lick an object picked up from the floor. Helminthiasis is accompanied by weakness, stool problems, frequent colds, nervousness, headache and other symptoms. Diagnosis of helminthiasis is possible only through stool examination.

If helminthiasis has been established, the doctor prescribes special drugs that have a detrimental effect on the parasites and remove them along with waste products from the body.

One of the drugs that can be prescribed in childhood is Pirantel. It is produced in the form of a suspension, which makes it easier for children to take.

In this article we will consider in detail the action, contraindications and side effects of the Pirantel suspension according to the instructions.

Compound

The active substance is called pyrantel pamoate. Each milliliter of the drug contains 50 mg of the active ingredient.

To ensure that the drug does not lose its properties, does not deteriorate and has a pleasant taste, its composition is supplemented with auxiliary components, namely sucrose, glycerol, water, sorbitol, simethicone emulsion, sodium benzoate, flavoring and other substances. You must carefully read the composition before use, as the child may be allergic to one of the components.

Properties

"Pyrantel" has a wide spectrum of action aimed at various types of helminths. The drug provokes a neuromuscular blockade in parasites, thereby helping to get rid of them.

Paralyzed helminths are eliminated from the body naturally through feces. The drug does not affect the functioning of the intestines in any way; its use does not lead to obstruction or intestinal spasms.

According to the instructions for use, Pyrantel suspension can also be prescribed for prophylaxis.

There are a number of helminths on which the drug acts with the highest degree of effectiveness. These include:

Pinworms. They cause enterobiasis, one of the most common types of parasites.
Roundworms. Round worms that provoke the development of ascariasis. They are localized in the small intestine.
Duodenal hookworm. A round-shaped helminth that causes hookworm infection.
New World hookworm. This parasite causes the development of necatoriasis.
Trichostrongylide. Causes trichostrongylosis and has a round shape.

The drug is not actually absorbed by the intestines. It is partially absorbed in the liver, so problems with this organ may cause refusal to take Pirantel. The active substance of the drug is active against both mature forms of helminths and parasites in the development stage, but its effect does not extend to moving larvae.

Indications

As the instructions indicate, the Pirantel suspension is prescribed for the following types of helminthiasis:

Enterobiasis. Quite often it is diagnosed in children. Signs of the disease are itching in the anus and intestinal upset.
Ascariasis. This type of helminthiasis is accompanied by a lethargic state, a slight increase in body temperature, decreased appetite, nausea, cough and other symptoms.
Ankylostomiasis. Symptoms of this disease include skin rashes, fever, bloating, nausea, diarrhea, etc.
Nekatoroz. Manifested by dyspepsia, anemia and allergic reactions.

The medication is prescribed not only when parasites are detected in the body, but also as a preventive measure when helminths are detected in another family member.

Overdose

So far there have been no reported cases of toxic effects of the drug when the dosage is exceeded. Experts agree that if a child accidentally drinks more than the dose prescribed for his age, it is necessary to induce vomiting in order to remove the drug from the body before it enters the intestines.

Next, you need to monitor the patient’s condition so that if it worsens, call a doctor. According to the instructions for use, adults and children should not take Pirantel suspension simultaneously with Piperazine, as this combination will weaken the therapeutic effect of both drugs.

Also, you cannot combine the suspension with other anthelmintic drugs, as this will increase the load on the liver.

In addition, manufacturers warn consumers against combining Pyrantel and theophylline, as this may cause an increase in the concentration of the latter and lead to the development of side effects.

Instructions and dosage

What else is included in the instructions for the Pirantel suspension? You should take the drug following these rules:

1. Quite often, the drug is prescribed for a single dose, that is, the prescribed dosage is not divided into several times, but is drunk once. Some particularly severe helminth infections may require a course of treatment of several days, but this is only permissible as prescribed by the attending physician.

2. Before taking, shake the bottle with the suspension well until smooth. If several doses are prescribed, the bottle must be shaken before each use.

3. The drug can be taken at any convenient time of the day. It should not be taken in the morning on an empty stomach or combined with laxatives.

4. Children are recommended to give the suspension with food or immediately after meals. For prophylactic purposes, the drug can be taken three weeks after the first use. This will help avoid relapse.

5. If pinworms are found in a child, treatment should be carried out on all family members in contact with the infected person.

6. Some time after taking Pirantel, it is necessary to conduct a control stool analysis.

The dosage of the drug for ascariasis or enterobiasis is determined individually, taking into account the age and weight of the patient. Typically, the calculation is made by multiplying the child's weight by 10 mg.

There is also a standard scheme for using the drug by age:

1. Up to two years of age, a child weighing less than 12 kg is prescribed 2.5 ml of suspension.

2. Up to six years of age, a child should be given 5 ml of the drug.

3. Up to 12 years of age, a single dosage is 10 ml.

4. After 12 years, 15 ml is prescribed for a single dose. This information is available in the instructions for the Pirantel suspension.

Dosage for different ages

The dosage should be calculated individually, based on the age and weight of the individual child. The suspension should be taken once a day after or during meals.

Let's take a closer look at how often you can give Pyrantel suspension to children, how to take the drug correctly and for how many days.

If ascariasis or enterobiasis is observed, give a suspension once a day at the rate of 10 mg per 1 kg of child weight.

Young children aged from six months to two years are prescribed 125 mg of suspension.

Children from two to six years old are prescribed 250 mg.

If your child is between 6 and 12 years old, then he should be given 500 mg of suspension.

Children over 12 years of age should take at least 750 mg. If the weight exceeds 75 kg, then the dose must be increased to 1 gram.

If hookworm is diagnosed, the course of treatment lasts 3 days, 10 mg per 1 kg per day is prescribed.

The treatment regimen may be slightly changed, i.e. the course will last two days, but the dose will have to be increased exactly twice - 20 mg per 1 kg of the patient’s weight.

One measuring spoon included in the kit contains 250 mg, which is very convenient for calculating the dosage.

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Side effects of Pirantel: pain, nausea, fever

Pyrantel, along with albendazole and mebendazole, is one of the three most widely used anthelmintic drugs.
The proven effectiveness and extremely low price of Pyrantel for many people become reasons to drink this remedy not only as prescribed by a doctor, but also on a regular basis as a preventive measure. But is such a tactic reasonable in relation to a drug that is associated with cases of leukemia (blood cancer) in children, not to mention two dozen not so serious side effects? Let's look at what exactly is the toxicity of Pirantel, what consequences its use entails, what to do if side effects occur, and what people's reviews say about this anthelmintic.

Harm of the drug

Like all chemical anthelmintics, Pirantel is harmful not only to parasites, but also to their hosts, which manifests itself in a whole bunch of side effects.

The most common of them, according to the observations of doctors and reviews of patients, are digestive problems: nausea, sometimes turning into vomiting; sharp stomach pain and pain in the lower abdomen; temporary disturbances in the sense of smell and taste; elevated temperature, which can last a long time - up to several days. Less common are allergic reactions (the appearance of a profuse red rash on the face) and central nervous system disorders (dizziness, insomnia and severe fatigue for several days).

Although, in comparison with albendazole and mebendazole (which can cause dangerous blood diseases such as neutropenia, thrombocytopenia and leukopenia), pyrantel was recognized as a gentle anthelmintic, it should be taken with precise dosage. Thus, a three-day course of treatment for hookworm is designed specifically for the gradual destruction of parasites. Exceeding the dose of the drug will provoke the immediate death of most of the helminths, which will cause severe poisoning of the body.

Cases of death of animals have been described after incorrect calculation of the dose of an antiparasitic agent: death not due to the action of the substance, but rather due to severe intoxication with the destruction products of worms.

The full list of side effects is as follows:

migraine;
sleep disturbance;
increased fatigue;
dizziness;
paresthesia;
decreased hearing acuity;
confusion;
hallucinations;
anorexia;
nausea;
vomit;
stomach pain;
diarrhea;
increased activity of transaminases in the liver;
skin itching;
exanthema;
hives.

The rarest and at the same time the most dangerous consequence of taking Pirantel is the development of leukemia.

The toxicity of the substance forces doctors to be extremely careful when prescribing Pirantel to pregnant women. For children under six months of age and in parallel with breastfeeding, this drug is never used.

What to do if side effects occur

Treatment in this case is symptomatic - i.e. depends on the body’s specific reactions to Pirantel.

The most universal remedy is enterosorbents - drugs that absorb toxic substances (in this case from the death of helminths) in the gastrointestinal tract. They are taken for nausea, vomiting, and fever after Pirantel. These include:

Activated carbon;
diosmectite (Smecta);
Polysorb
Enterosgel
kaolin, etc.

If headaches occur and you cannot simply wait them out, you can take analgesics based on paracetamol and caffeine: '

Solpadeine;
Caffetin;
Migrenol, etc.

Insomnia that occurs after taking Pirantel can be eliminated with such over-the-counter and relatively safe sleeping pills as:

Melaxen;
Donormil;
Novo-Passit;
Corvalol.

Intoxication of the body with decay products of killed parasites deserves special mention. If there is no effect from conventional enterosobrents, the doctor may prescribe a suitable detoxifying agent. This symptom indicates a strong infestation, and in order to avoid further poisoning, it is better to continue the treatment course with natural plant-based antiparasitic agents.

Reviews about the drug

Although in most cases treatment with Pyrantel is very “painless”, severe infestations and individual reactions of the body can cause unpredictable and long-lasting consequences. This is exactly what the following reviews collected on the Internet demonstrate.

Edward: “I found pinworms in the stool, it seems. I didn’t go to the doctors, I decided to take Pirantel myself. The next day after taking it, for some reason the itching in the anus intensified, and in addition, it became worse: I felt nauseous, the temperature rose to 37.2 and is still there.”

Anna: “Three cats live at home, so I decided to worm myself just in case. I bought Pirantel and after taking it I realized how good it was that I didn’t give it to cats. At first I felt hot and sweaty, but soon it stopped.

Then the right side of my body became swollen, and now my stomach hurts. It's like there's a tug in the lower abdomen. Shortness of breath began. It's the second week, the abdominal pain is still there. I do not know what to do. And the pharmacy assured that there were no drugs safer than Pirantel.

I’m afraid to think what side effects others have.”

Valentina: “The pediatrician prescribed Pirantel for my son after an analysis revealed ascariasis and enterobiasis in the child. I gave the child half a tablet. The day passed as usual. The next evening, my son’s temperature rose and lasted for a long time, until the morning.

The child hardly slept, drank water every half hour, and began vomiting in the morning. The next analysis did not find worm eggs in the stool. Conclusion: the remedy is effective, but for those who value their health, it is better to be treated under the supervision of a doctor.

Poorly suited for prevention."

Pyrantel is a relatively mild anthelmintic, but it is not without the toxicity inherent in such drugs. The unpredictability of the consequences forces the use of Pirantel only as prescribed by a parasitologist and only after detection of real helminthiasis.

Source: https://gelmintov.net/lekarstva/pobochnye-dejstviya-pirantela.html

Overdose and side effects

So far , not a single case of drug overdose has been recorded, i.e. it can be taken absolutely calmly, based on the correct dosage.

Possible side effects:

from the liver and gastrointestinal tract - vomiting, nausea, diarrhea and stomach pain;
from the central nervous system - insomnia, feeling of drowsiness, headaches, general weakness, dizziness. Cases were identified in which hallucinations, hearing impairment and spatial orientation were manifested;
in some cases, the child may experience an allergic reaction, rash and fever.